University of Southern California

McMahon Lab

USC Stem Cell


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Andy McMahon quoted in the San Diego Union Tribune

Andy McMahon offered his perspective in the article “Will President Trump restrict embryonic stem cell research funding?” in the San Diego Union Tribune. To read the article, visit

What I’m Reading: Andy McMahon and Gage Crump offer top picks

Gage Crump: In the latest issue of Science Translational Medicine, Katja M. Heinemeier and coauthors use “bomb pulse” labeling to provide new insights into cell turnover in our joints. This technique takes advantage of the temporary high radiation levels in […]

Hironori Hojo and colleagues illuminate bone formation and vertebrate evolution

With the emergence of bone, the diversity of life expanded to encompass the bone-forming vertebrates, a group of species ranging from the tiny frog Paedophryne amauensis to the mighty blue whale. Bone formation in vertebrates is linked to a shared […]

Andy McMahon honored at UKRO benefit gala

University Kidney Research Organization (UKRO) honored USC academic and scientific leaders at its sixth gala dinner March 18 at The Beverly Hilton, with 300 attendees. This group of vocal champions of kidney disease research included Provost and Senior Vice President […]

Lori O’Brien and colleagues identify key difference between mouse and human kidney cells

The best laid plans of mice and men are a bit different — at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans […]

Albert Kim receives first Hearst Fellowship

How do you turn stem cells into nephrons, the functional unit of the kidney? Albert D. Kim, a postdoctoral fellow in the McMahon Lab, is exploring this question with support from a Hearst Fellowship, an award recognizing an exceptional junior […]

Sanjeev Kumar describes how Sox9 kicks injured kidney cells into reparative mode

In the kidney, injured cells can be kicked into reparative mode by a gene called Sox9, according to a new paper published in Cell Reports. First author Sanjeev Kumar, a postdoctoral research associate in the USC Stem Cell laboratory of […]

Xinjun He and colleagues reveal a genetic blueprint for cartilage

Cartilage does a lot more than determine the shapes of people’s ears and noses. It also enables people to breathe and to form healthy bones — two processes essential to life. In a study published in Cell Reports, McMahon Lab […]

Lori O’Brien receives first Broad Fellowship

What makes stem cells develop into kidneys? Lori O’Brien, a postdoctoral research associate in the laboratory of Andy McMahon, has received the first Broad Fellowship to help answer this question. To read more, visit

Jing Liu and colleagues lay a TRAP for disease

USC Stem Cell scientists have set a “mouse TRAP” to capture the early signs of kidney failure, as described by a recent study published in the Journal of Clinical Investigation. Their new transgenic mouse line uses a technique called TRAP […]