The best laid plans of mice and men are a bit different — at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans […]
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How do you turn stem cells into nephrons, the functional unit of the kidney? Albert D. Kim, a postdoctoral fellow in the McMahon Lab, is exploring this question with support from a Hearst Fellowship, an award recognizing an exceptional junior […]
In the kidney, injured cells can be kicked into reparative mode by a gene called Sox9, according to a new paper published in Cell Reports. First author Sanjeev Kumar, a postdoctoral research associate in the USC Stem Cell laboratory of […]
Cartilage does a lot more than determine the shapes of people’s ears and noses. It also enables people to breathe and to form healthy bones — two processes essential to life. In a study published in Cell Reports, McMahon Lab […]
What makes stem cells develop into kidneys? Lori O’Brien, a postdoctoral research associate in the laboratory of Andy McMahon, has received the first Broad Fellowship to help answer this question. To read more, visit stemcell.usc.edu/2014/11/10/usc-stem-cell-researcher-lori-obrien-receives-the-first-broad-fellowship.
USC Stem Cell scientists have set a “mouse TRAP” to capture the early signs of kidney failure, as described by a recent study published in the Journal of Clinical Investigation. Their new transgenic mouse line uses a technique called TRAP […]
Sanjeev Kumar, a postdoctoral research associate in the lab, shared his research about the role of Sox9 in repairing acute kidney injuries at the Tri-Institutional Stem Cell Retreat of the Eli and Edythe Broad Centers for Regenerative Medicine and Stem […]
At an April 16 TEDx event, Dr. Andy McMahon introduced students to USC stem cell research that could lead to treatments for macular degeneration, HIV, neurodegeneration and kidney disease.
The McMahon lab and the Senta Georgia lab at Children’s Hospital Los Angeles co-hosted a BCC Mixer on February 28 from 4–5 p.m. in the fourth floor conference room. To view photos from the event, visit flickr.com/photos/106541334@N04/sets/72157641964373573.
Can patients with kidney disease be effectively treated with injections of stem cells or other cells that aren’t fully differentiated? Chinese businessman Yong Chen has pledged $400,000 to begin answering this question. To read more, visit stemcell.usc.edu/2014/02/11/businessman-invests-in-usc-stem-cell-kidney-disease-team.