University of Southern California

McMahon Lab

USC Stem Cell


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Sanjeev Kumar describes how Sox9 kicks injured kidney cells into reparative mode

In the kidney, injured cells can be kicked into reparative mode by a gene called Sox9, according to a new paper published in Cell Reports. First author Sanjeev Kumar, a postdoctoral research associate in the USC Stem Cell laboratory of […]

Xinjun He and colleagues reveal a genetic blueprint for cartilage

Cartilage does a lot more than determine the shapes of people’s ears and noses. It also enables people to breathe and to form healthy bones — two processes essential to life. In a study published in Cell Reports, McMahon Lab […]

Lori O’Brien receives first Broad Fellowship

What makes stem cells develop into kidneys? Lori O’Brien, a postdoctoral research associate in the laboratory of Andy McMahon, has received the first Broad Fellowship to help answer this question. To read more, visit

Jing Liu and colleagues lay a TRAP for disease

USC Stem Cell scientists have set a “mouse TRAP” to capture the early signs of kidney failure, as described by a recent study published in the Journal of Clinical Investigation. Their new transgenic mouse line uses a technique called TRAP […]

Sanjeev Kumar speaks at tri-institutional stem cell retreat

Sanjeev Kumar, a postdoctoral research associate in the lab, shared his research about the role of Sox9 in repairing acute kidney injuries at the Tri-Institutional Stem Cell Retreat of the Eli and Edythe Broad Centers for Regenerative Medicine and Stem […]

Dr. McMahon speaks at USC TEDx event

At an April 16 TEDx event, Dr. Andy McMahon introduced students to USC stem cell research that could lead to treatments for macular degeneration, HIV, neurodegeneration and kidney disease.

Lab co-hosts BCC Mixer

The McMahon lab and the Senta Georgia lab at Children’s Hospital Los Angeles co-hosted a BCC Mixer on February 28 from 4–5 p.m. in the fourth floor conference room. To view photos from the event, visit

Businessman invests in USC Stem Cell Kidney Disease Team

Can patients with kidney disease be effectively treated with injections of stem cells or other cells that aren’t fully differentiated? Chinese businessman Yong Chen has pledged $400,000 to begin answering this question. To read more, visit

Andrew McMahon is teaching BISC 499 in Spring 2014.

This course focuses on general mechanistic principles that underpin development, maintenance and repair of body systems from worms to man. We discuss critical experimental studies that frame the current view of animal organization, and the application of knowledge gained to […]

McMahon Lab welcomes Linda (Can) Lu and Peter Whitney

The McMahon Lab welcomes two new members: Linda (Can) Lu, a student from Xiangya Medical School in China; and research lab technician Peter Whitney.