Kidney images

McMahon and collaborators tune into the organ concert

Every minute of every day, your organs are using a complex language to communicate with each other about the basic physiological processes necessary for life—everything from blood pressure regulation to pH balance to metabolism. To decipher this little-known language, USC Stem Cell scientist Andy McMahon has joined forces with top scientists at Harvard and Stanford…Continue Reading McMahon and collaborators tune into the organ concert

From perfectly punctual to fashionably late, it takes all kinds to build a kidney

Running early or running late can have big consequences—especially when it comes to the progenitor cells involved in human kidney development. According to a new study in Developmental Cell from the USC Stem Cell laboratory of Andy McMahon, the progenitor cells that form the kidney’s filtering units, called nephrons, mature into entirely different types of…Continue Reading From perfectly punctual to fashionably late, it takes all kinds to build a kidney

Growing hope: New organs? Not yet, but stem cell research is getting closer

  If you lose a limb, it’s lost for life. If you damage a kidney, you won’t grow a new one. And if you have a heart attack, the scars are there to stay. But regenerative medicine is poised to change all of this. Building new tissue is within sight, and USC scientists are among…Continue Reading Growing hope: New organs? Not yet, but stem cell research is getting closer

Nils Lindstrom and colleagues publish new research in the Journal of the American Society of Nephrology

Researchers are hard at work building mini-kidneys from human cells—using blueprints mostly drawn from lab mice. But mouse kidneys differ from their human counterparts in more than mere scale, as detailed by the USC Stem Cell laboratory of Andy McMahon in three studies in the Journal of the American Society of Nephrology. “In mice, the…Continue Reading Nils Lindstrom and colleagues publish new research in the Journal of the American Society of Nephrology