Recent Publications

  1. Tran, T, Lindström, NO, Ransick, A, De Sena Brandine, G, Guo, Q, Kim, AD et al.. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev. Cell. 2019;50 (1):102-116.e6. doi: 10.1016/j.devcel.2019.06.001. PubMed PMID:31265809 PubMed Central PMC6684316.
  2. Rutledge, EA, Parvez, RK, Short, KM, Smyth, IM, McMahon, AP. Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev. Biol. 2019; :. doi: 10.1016/j.ydbio.2019.06.012. PubMed PMID:31242448 .
  3. Cippà, PE, Liu, J, Sun, B, Kumar, S, Naesens, M, McMahon, AP et al.. A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019;10 (1):1157. doi: 10.1038/s41467-019-09092-2. PubMed PMID:30858375 PubMed Central PMC6411919.
  4. Menshykau, D, Michos, O, Lang, C, Conrad, L, McMahon, AP, Iber, D et al.. Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nat Commun. 2019;10 (1):239. doi: 10.1038/s41467-018-08212-8. PubMed PMID:30651543 PubMed Central PMC6484223.
  5. O'Brien, LL, Combes, AN, Short, KM, Lindström, NO, Whitney, PH, Cullen-McEwen, LA et al.. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018;7 :. doi: 10.7554/eLife.40392. PubMed PMID:30516471 PubMed Central PMC6281319.
  6. Cippà, PE, Sun, B, Liu, J, Chen, L, Naesens, M, McMahon, AP et al.. Transcriptional trajectories of human kidney injury progression. JCI Insight. 2018;3 (22):. doi: 10.1172/jci.insight.123151. PubMed PMID:30429361 PubMed Central PMC6302941.
  7. Lindström, NO, De Sena Brandine, G, Ransick, A, McMahon, AP. Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am. J. Kidney Dis. 2019;73 (1):140-142. doi: 10.1053/j.ajkd.2018.07.002. PubMed PMID:30241960 PubMed Central PMC6480390.
  8. Hasenpusch-Theil, K, West, S, Kelman, A, Kozic, Z, Horrocks, S, McMahon, AP et al.. Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018;145 (17):. doi: 10.1242/dev.163147. PubMed PMID:30093555 PubMed Central PMC6141774.
  9. Przepiorski, A, Sander, V, Tran, T, Hollywood, JA, Sorrenson, B, Shih, JH et al.. A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells. Stem Cell Reports. 2018;11 (2):470-484. doi: 10.1016/j.stemcr.2018.06.018. PubMed PMID:30033089 PubMed Central PMC6092837.
  10. Lindström, NO, De Sena Brandine, G, Tran, T, Ransick, A, Suh, G, Guo, J et al.. Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev. Cell. 2018;45 (5):651-660.e4. doi: 10.1016/j.devcel.2018.05.010. PubMed PMID:29870722 PubMed Central PMC6510587.