Recent Publications

  1. Liu, J, Kumar, S, Heinzel, A, Gao, M, Guo, J, Alvarado, GF et al.. Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury. J. Am. Soc. Nephrol. 2020;31 (4):701-715. doi: 10.1681/ASN.2019090876. PubMed PMID:32034106 PubMed Central PMC7191932.
  2. Rutledge, EA, McMahon, AP. Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev. Dyn. 2020; :. doi: 10.1002/dvdy.157. PubMed PMID:32017326 .
  3. Rutledge, EA, Lindström, NO, Michos, O, McMahon, AP. Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev. Biol. 2020;458 (2):164-176. doi: 10.1016/j.ydbio.2019.11.007. PubMed PMID:31734175 PubMed Central PMC6995766.
  4. Ransick, A, Lindström, NO, Liu, J, Zhu, Q, Guo, JJ, Alvarado, GF et al.. Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev. Cell. 2019;51 (3):399-413.e7. doi: 10.1016/j.devcel.2019.10.005. PubMed PMID:31689386 PubMed Central PMC6948019.
  5. Kim, AD, Lake, BB, Chen, S, Wu, Y, Guo, J, Parvez, RK et al.. Cellular Recruitment by Podocyte-Derived Pro-migratory Factors in Assembly of the Human Renal Filter. iScience. 2019;20 :402-414. doi: 10.1016/j.isci.2019.09.029. PubMed PMID:31622881 PubMed Central PMC6817668.
  6. Tran, T, Lindström, NO, Ransick, A, De Sena Brandine, G, Guo, Q, Kim, AD et al.. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev. Cell. 2019;50 (1):102-116.e6. doi: 10.1016/j.devcel.2019.06.001. PubMed PMID:31265809 PubMed Central PMC6684316.
  7. Rutledge, EA, Parvez, RK, Short, KM, Smyth, IM, McMahon, AP. Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev. Biol. 2019;454 (2):156-169. doi: 10.1016/j.ydbio.2019.06.012. PubMed PMID:31242448 PubMed Central PMC6726516.
  8. Cippà, PE, Liu, J, Sun, B, Kumar, S, Naesens, M, McMahon, AP et al.. A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019;10 (1):1157. doi: 10.1038/s41467-019-09092-2. PubMed PMID:30858375 PubMed Central PMC6411919.
  9. Menshykau, D, Michos, O, Lang, C, Conrad, L, McMahon, AP, Iber, D et al.. Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback. Nat Commun. 2019;10 (1):239. doi: 10.1038/s41467-018-08212-8. PubMed PMID:30651543 PubMed Central PMC6484223.
  10. O'Brien, LL, Combes, AN, Short, KM, Lindström, NO, Whitney, PH, Cullen-McEwen, LA et al.. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018;7 :. doi: 10.7554/eLife.40392. PubMed PMID:30516471 PubMed Central PMC6281319.